West Coast have named key trio Quentin Lynch, Beau Waters and Ashton Hams for Saturday's crunch clash with Adelaide at AAMI Stadium, while the Crows welcome back key forward Kurt Tippett.
Tippett, who missed last week's hammering of GWS with concussion, comes in along with defender Graham Johncock, Michael Doughty and Jared Petrenko for Adelaide, who are only percentage off top spot, while the Eagles are eying a return to the top four after slipping out for the first time this season following their 52-point loss to Sydney last week.
The Crows also welcome back Brad Symes and Andy Otten but have lost Chris Knights, Brodie Martin (hamstring), Ricky Henderson (ankle) and Sam Shaw (eye) to injury.
The Eagles have omitted defender Mitch Brown, Koby Stevens and Thomas Swift but will be thankful to welcome back three key players after a tough run with injuries.
Star midfielder Dustin Martin returns for Richmond following a two-week, club-imposed ban that saw the sacking of team-mate Daniel Connors after the pair missed training.
Daniel Jackson also comes in for the Tigers' battle for a top-eight spot with North Melbourne, who have included Levi Greenwood, Cruize Garlett and Ben Cunnington for suspended midfielder Jack Ziebell.
The Magpies have named young defender Tom Young and midfielder Paul Seedsman for Martin Clarke and Simon Buckley (both omitted) for Saturday's blockbuster clash with Hawthorn, who are unchanged.
In the absence of injured star forward Lance Franklin, defender Ryan Schoenmakers is expected to be handed more time up forward for the Hawks, while captain Luke Hodge is named to play for VFL affiliate Box Hill.
Essendon have included key forward Stewart Crameri after a two-week suspension and Angus Monfries to bolster their attack for Friday night's danger game with Geelong.
Kyle Reimers (hamstring) and Michael Hibberd (quad) are the two to miss out.
The Cats, meanwhile, have made one change with Jordan Murdoch replacing the injured Allen Christensen (shoulder).
Carlton and the Western Bulldogs have made a host of changes for their clash on Saturday night at Etihad Stadium.
The Dogs have included forwards Daniel Giansiracusa and Jarrad Grant, ex-Swan Patrick Veszpremi, Daniel Pearce and Mark Austin at the expense of defenders Lukas Markovic (hamstring) and Ryan Hargrave, forward Justin Sherman, Clay Smith (calf) and Tory Dickson (adductor).
The Blues lose captain Chris Judd to suspension and have been hit hard with key injuries to ruckman Matthew Kreuzer (hip), Andrew Walker (calf), defender Lachlan Henderson (groin) and Kane Lucas (hamstring).
Paul Bower, Jordan Russell, Bret Thornton and debutants Levi Casboult and Tom Bell have been named.
Gold Coast have included Luke Russell and Tom Lynch for Saturday's Queensland derby with Brisbane, with the Lions naming Jarred Polec and Ryan Lester for the suspended Daniel Rich.
Neville Jetta comes in for Melbourne for his first game in 2012, along with Lynden Dunn, Jake Spencer and mature-aged recruit James Magner.
Matthew Bate, Mark Jamar (calf), Jamie Bennell (knee) and Jordie McKenzie (groin) miss out for the Dees for their encounter with Port Adelaide at Darwin's TIO Stadium.
Captain Domenic Cassisi and Jasper Pittard come in for the Power with Jarrad Redden and Darren Pfeiffer omitted.
Brendon Goddard is back in for St Kilda along with Jack Steven and Terry Milera as they try to beat Sydney for the second time this season.
The Swans have named Trent Dennis-Lane, Tony Armstrong and Tommy Walsh, with neither side listing any outs as of yet.
Fremantle have brought in Zac Clarke and Jay van Berlo among five ins for Sunday's match with GWS at Patersons Stadium, with forward Chris Mayne (calf) and defender Greg Broughton (back) missing out.
Kevin Sheedy has wrung the changes yet again with 11 inclusions: Kurt Aylett, Josh Bruce, Tomas Bugg, Jonathan Giles, Anthony Miles, Andrew Phillips, Jacob Townsend, Gerald Ugle, Mark Whiley, William Hoskin-Elliot and Sam Frost.
Making way are tall forwards Jeremy Cameron (back) and Jonathon Patton, midfielder Stephen Coniglio (back), Taylor Adams, Devon Smith, Dean Brogan (rested), Chad Cornes (rested) and Adam Kennedy (illness).
North Ballarat recruit Aylett, Ugle (Perth) and Frost (Sandringham Dragons) are all in line to debut.
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